publications
Clark, A., Thomas, K.R., Ortega, N., Haley, A.P. ‡, Duarte, A., O’Bryant, S. Precision health approach to HABS-HD: Empirically derived psychosocial phenotypes, AD biomarkers, and cognitive outcomes of Black and Latino older adults. Alzheimer’s & Dementia (accepted).
Haley, A.P. ‡, Clark, A.L., Duarte, A. (2023). Lower body mass index at baseline is related to steeper cognitive decline in the Alzheimer’s Disease Neuroimaging Initiative (ADNI) cohort. Psychosomatic Medicine, Aug 21. doi: 10.1097/PSY.0000000000001245. Online ahead of print.
Foret, J.T.*, Gourley, D.D., Caillaud, M., Dekhtyar, M.*, Tanaka, H., Haley, A.P. ‡ (2022). Influence of endogenous estrogen on a network model of female brain integrity. Aging Brain, Oct 14;2:100053. doi: 10.1016/j.nbas.2022.100053. eCollection 2022
Clark, A., Haley, A.P. ‡, Duarte, A., O’Bryant, S. (2022). Fatty Acid-Binding Protein 3 is a marker of neurodegeneration and white matter hyperintensity burden in Hispanic/Latino older adults. Journal of Alzheimer’s Disease, 90(1):61-68.
Dekhtyar, M.*, Foret, J.T*., Simon, S**., Shumake, J., Clark, A., Haley, A.P. ‡ (2022). An examination of the clinical utility of phonemic fluency in healthy adults and adults with Mild Cognitive Impairment. Applied Neuropsychology: Adult, Apr 19;1-9, doi: 10.1080/23279095.2022.2061860. Online ahead of print.
Foret, J.T.*, Dekhtyar, M.*, Birdsill, A.C., Tanaka, H., Haley, A.P. ‡ (2021). Metabolic Syndrome components moderate the association between executive function and functional connectivity in the default mode network. Brain Imaging and Behavior, 15(4):2139-2148.
Foret, J.T.*, Dekhtyar, M.*, Cole, J.H., Gourley, D.D.*, Caillaud, M., Tanaka, H., Haley, A.P.‡ (2021). Network modeling sex differences in brain integrity and metabolic health. Frontiers of Aging Neuroscience, 13:691691. doi: 10.3389/fnagi.2021.691691. eCollection 2021.
Foret, J.T.*, Oleson, S., Hickson, B.*, Valek, S.**, Tanaka, H., Haley, A.P. ‡ (2021). Metabolic Syndrome and cognitive function in midlife. Archives of Clinical Neuropsychology, 36(6):897-907.
Gourley, D.*, Pasha, E.P., Kaur, S., Haley, A.P., Tanaka, H. ‡ (2020). Association of dementia and vascular risk scores with cortical thickness and cognition in low-risk, middle-aged adults. Alzheimer Disease & Associated Disorders, 34(4): 313-317.
Haley, A.P. (2020). Obesity and the brain: Another brain-body vs. body-brain conundrum. Psychosomatic Medicine, 82(3), 258-260.
Henneghan, A. ‡, Haley, A.P., Kessler, S. (2020). Exploring relationships among peripheral amyloid beta, tau, cytokines, cognitive function and psychosocial symptoms in breast cancer survivors. Biological Research for Nursing, 22(1), 126-138.
Oleson, S.*, Eagan, E.*, Kaur, S.*, Hertzing, W.J.**, Alkatan, M.*, Davis, J.N., Tanaka, H., Haley, A.P. ‡ (2020). Apolipoprotein E genotype moderates the association between dietary polyunsaturated fat and brain function: an exploration of cerebral glutamate and cognitive performance. Nutritional Neuroscience, 23(9):696-705.
Tanaka, H. ‡, Gourley, D.*, Dekhtyar, M.*, Haley, A.P. (2020). Cognition, brain structure, and brain function in individuals with obesity and related disorders. Current Obesity Reports, 9(4):544-549.
Cassill, C.**, Steward, K., Eagan, D., Kaur, S., Kruzliak, P., Haley, A.P. (2018). Depressive symptoms exacerbate the effects of HSV-1 infection on cognitive function in middle age. Journal of Clinical and Infectious Disease and Practice, 3:1. doi: 10.4172/2476- 213X.1000122
Haley, A.P., Oleson, S., Pasha, E., Birdsill, A., Kaur, S., Thompson, T., Tanaka, H. (2018). Phenotypic heterogeneity of obesity-related brain vulnerability: One-size interventions will not fit all. Annals of The New York Academy of Sciences. [Epub ahead of print]. doi: 10.1111/nyas.13673.
Pasha, E.P.*, Birdsill, A.C., Oleson, S., Haley, A.P., Tanaka, H. (2018a). Physical activity mitigates adverse effects of Metabolic Syndrome on vessels and brain. Brain Imaging and Behavior. [Epub ahead of print]. doi: 10.1007/s11682-018-9830-3.
Pasha, E.P.*, Birdsill, A.C., Oleson, S., Tanaka, H., Haley, A.P. (2018b). Midlife carotid arterial compliance and white matter diffusion metrics during midlife: Modulation by sex. Neurobiology of Aging. [Epub ahead of print]. doi: 10.1016/j.neurobiolaging.2018.02.012.
Birdsill, A.C.*, Kaur, S., Pasha, E., Oleson, S., Ireton, A., Tanaka, H., Haley, A.P. (2017). Obesity-related differences in regional white matter microstructure in midlife. Human Brain Mapping, Apr 8. doi: 10.1002/hbm.23576. [Epub ahead of print].
Laosiripisan, J.*, Haley, A.P., Tanaka, H. (2017). Steady state vs. pulsatile blood pressure component and regional cerebral perfusion. American Journal of Hypertension, 30(11), 1100-1105.
Kaur, S.*, Birdsill, A.C., Steward, K., Pasha, E., Kruzliak, P., Tanaka, H., Haley, A.P. (2017) Higher visceral fat is associated with lower cerebral N-acetyl-aspartate ratios in middle-aged adults. Metabolic Brain Disease, 32(3), 727-733.
Pasha, E.P.*, Birdsill, A., Parker, P., Elmenshawy, A., Tanaka, H., Haley, A.P. (2017a). Visceral adiposity predicts subclinical white matter hyperintensities in middle-aged adults. Obesity Research and Clinical Practice, 11(2),177-187.
Pasha, E.P.*, Birdsill, A.C., Oleson, S., Haley, A.P., Tanaka, H. (2017b). Impacts of Metabolic Syndrome scores on cerebrovascular conductance are mediated by arterial stiffening. American Journal of Hypertension, 31(1), 72-79.
Pasha, E.P.*, Tarumi, T., Haley, A.P., Tanaka, H. (2017c). Transcranial Doppler of the middle cerebral artery indicates regional gray matter cerebral perfusion. Physiological Measurement, 38(12), 2176-2185.
Vargas, E.*, Barrett, D.W., Saucedo, C.L., Huang, L-D., Abraham, J.A., Tanaka, H., Haley, A.P., Gonzalez-Lima, F. (2017). Beneficial neurocognitive effects of transcranial laser in older adults. Lasers in Medical Science, 32(5), 1153-1162.
Oleson, S.*, Tarumi, T., Gonzales, M.M., Davis, J., Tanaka, H., Haley, A.P. (2016). Nutrient intake and cerebral metabolism in healthy middle-aged adults: implications for cognitive aging. Nutritional Neuroscience, 20(8), 489-496.
Kaur, S.*, Gonzales, M.M., Tarumi, T., Villaplando, A., Alkatan, M., Pyron, M., Tanaka, H., Haley, A.P. (2016). Serum Brain-Derived Neurotrophic Factor mediates the relationship between abdominal obesity and executive function in middle age. Journal of the International Neuropsychological Society, 22(5), 493-500.
Kobyliak, N., Conte, C., Cammarota, G., Haley, A.P., Styriak, I., Gaspar, L., Fusek, J., Rodrigo, L., Kruzliak, P. (2016). Probiotics in prevention and treatment of obesity: a critical review. Nutrition & Metabolism, 13:14. doi 10.1186/s12986-016-0067-0.
Tarumi, T.*, Gonzales, M.M., Fallow, B., Nualnim, N., Lee, J., Pyron, M., Tanaka, H., Haley, A.P. Cerebral/peripheral vascular reactivity and neurocognition in middle-age athletes. Medicine & Science in Sports & Exercise.
Haley, A. P., Alosco, M.L., Gunstad, J. (2015). Surgical and non-surgical interventions for obesity in service of preserving cognitive function. Psychosomatic Medicine, 77, 679-687.
Laosiripisan, J., Tarumi, T., Gonzales, M.M., Haley, A.P., Tanaka, H. (2015). Association between cardiovagal baroreflex sensitivity and basal cerebral perfusion at hippocampus. Clinical Autonomic Research. (DOI) 10.1007/s10286-015-0296-8.
Kaur, S.*, Gonzales, M. M., Pasha, E., Tanaka, H., Haley, A. P. ‡ (2015). Central adiposity and cortical thickness in mid-life. Psychosomatic Medicine. 2015 Jun 19. [Epub ahead of print]
Tarumi, T.*, Gonzales, M. M., Fallow, B., Nualnim, N., Lee, J., Tanaka, H., Haley, A. P. ‡ (2015). Cardiopulmonary fitness and cognitive function in middle age: associations with cerebral and peripheral vascular reactivity. Medicine & Science in Sports & Exercise. 2015 Jun 16. [Epub ahead of print]
Kruzliak, P, Haley, A.P., Starcevic, J.N., Gaspar, L., Petrovic, D. (2015). Polymorphisms of the Peroxisome Proliferator-Activated Receptor-γ (rs1801282) and its coactivator-1 (rs8192673) are associated with obesity indexes in subjects with type 2 diabetes mellitus. Cardiovascular Diabetology, 2015 Apr 28;14:42. Doi: doi: 10.1186/s12933-015-0197-0
Strasser, B., Arvandi, M., Pasha, E.P., Haley, A.P., Stanforth, P., Tanaka, H. (2015). Abdominal obesity is associated with arterial stiffness in middle-aged adults. Nutrition, Metabolism, and Cardiovascular Diseases, 25, 495-502.
Pasha, E.P.*, Kaur, S.S., Gonzales, M.M., Machin, D.R., Kasischke, K., Tanaka, H., Haley, A.P. (2015). Vascular function, cerebral cortical thickness, and cognitive performance in middle-aged Hispanic and non-Hispanic Caucasian adults. Journal of Clinical Hypertension (Greenwich), 17(4), 306-12.
Pasha, E.P.*, Haley, A.P., Tanaka, H. (2015). Ethnoracial disparities in Alzheimer’s disease: Target on cardiovascular risks via lifestyle changes? Journal of Gerontology and Geriatric Research, 3, 5.
Kaur, S.*, Eagan, D. E., Gonzales, M. M., Tarumi, T., Tanaka, H., Haley, A. P. (2015). Inflammation mediates reductions in cortical thickness in adults with Metabolic Syndrome. Brain Imaging and Behavior, Nov 7, [Epub ahead of print]
Haley, A. P. (2014). Vascular functions and brain integrity in midlife: Effects of obesity and metabolic syndrome. Advances in Vascular Medicine. Volume 2014, Article ID 653482, http://dx.doi.org/10.1155/2014/653482.
Gonzales, M.M.*, Kaur, S., Eagan, D.E., Goudzari, K., Pasha, E., Doan, D.C., Tanaka, H., Haley, A.P. (2014). Central adiposity and the functional magnetic resonance imaging response to cognitive challenge. International Journal of Obesity (London), 38(9), 1193-9.
Gonzales, M.M.*, Tarumi, T., Mumford, J.A., Ellis, R.C., Hungate, J.R., Pyron, M., Tanaka, H., Haley, A.P. (2014). Greater BOLD response to working memory in endurance-trained adults revealed by breath-hold calibration. Human Brain Mapping, 35(7), 2898-910.
Steward, K. A.*, Pasha, E., Goudarzi, K., Elmenshawy, A., Alkatan, M., Villaplando, A., Tanaka, H., Haley, A. P. ‡ (2013). Midlife arterial stiffness and brain activation during working memory task. The Open Hypertension Journal, 5, 00-00. Open Access.
Tarumi, T.*, Gonzales, M.M., Fallow, B., Nualnim, N., Pyron, M., Tanaka, H., Haley, A.P. (2013). Central artery stiffness, neuropsychological function, and cerebral perfusion in sedentary and endurance-trained middle-aged adults. Journal of Hypertension, 31(12), 2400-9.
Tarumi, T.*, Gonzales, M.M., Fallow, B., Nualnim, N., Lee, J., Tanaka, H., Haley, A.P. (2013). Aerobic fitness and cognitive function in midlife: an association mediated by plasma insulin. Metabolic Brain Disease, 28(4), 727-30.
Haley, A.P., Gonzales, M.M., Tarumi, T., Tanaka, H. (2013). Dyslipidemia links obesity to early cerebral neurochemical alterations. Obesity (Silver Spring), 21(10), 2007-13.
Gonzales, M.M.*, Tarumi, T., Kaur, S., Nualnim, N., Fallow, B.A., Pyron, M., Tanaka, H., Haley, A.P. (2013). Aerobic fitness and the brain: Increased N-acetyl-aspartate and choline concentrations in endurance-trained middle-aged adults. Brain Topography, 26(1), 126-34.
Gonzales, M.M.*, Tarumi, T., Eagan, D.E., Tanaka, H., Vaghasia, M., Haley, A.P. (2012) Indirect effects of elevated body mass index on memory performance through altered cerebral metabolite concentrations. Psychosomatic Medicine, 74(7), 691-698.
Sweet, L.H., Hassenstab, J.J., McCaffery, J.M., Raynor, H.A., Bond, D.S., Demos, K.E., Haley, AP, Cohen, R.A., Del Parigi, A., Wing, R.R. (2012). Brain response to food stimulation in obese, normal weight, and successful weight loss maintainers. Obesity, 20(11), 2220-5.
Haley, A.P., Gonzales, M.M., Tarumi, T., Tanaka, H. (2012). Subclinical vascular disease and cerebral glutamate elevation in Metabolic Syndrome. Metabolic Brain Disease, 27(4), 513-20.
Eagan, D.*, Gonzales, M.M., Tarumi, T., Tanaka, H., Stautberg, S., Haley, A.P. (2012). Elevated serum C-reactive protein relates to increased cerebral myo-Inositol levels in middle-aged adults. Cardiovascular Psychiatry and Neurology, 2012, 120540.
Hassenstab, J.J., Sweet, L.H., Del Parigi, A., McCaffery, J.M., Haley, A.P., Demos, K.E., Cohen, R.A., Wing, R.R. (2012) Cortical thickness of the cognitive control network in obesity and successful weight loss maintenance: A preliminary MRI study. Psychiatry Research: Neuroimaging, 202(1), 77-79.
Haley, A.P., Eagan, D.E., Gonzales, M.M., Biney, F.O., Cooper, R.A. (2011) fMRI of working memory reveals frontal hypoactivation in middle-aged adults with cognitive complaints. Journal of the International Neuropsychological Society, 17(5), 915-24.
Haley, A.P. (2011) Subclinical atherosclerosis and neuronal integrity in midlife. International Atherosclerosis Society [On-line].
Hoth, K.F., Gonzales, M.M., Tarumi, T., Miles, S.C., Tanaka, H., Haley, A.P. (2011) fMRI evidence of altered functional activation in Metabolic Syndrome. American Journal of Neuroradiology, 32(3), 541-547.
Gonzales M.M.*, Tarumi T, Eagan D, Tanaka H, Biney, F.O., Haley AP. (2011) Current serum lipoprotein levels and fMRI Response to working memory in midlife. Dementia and Geriatric Cognitive Disorders, 31(4), 259-267.
Tarumi, T.*, Shah, F., Tanaka, H., Haley, A.P. Association between central artery stiffness and cerebral perfusion in deep subcortical gray and white matter. American Journal of Hypertension, 24(10), 1108-13.
Haley, A.P. and Knight-Scott, J. Proton magnetic resonance spectroscopy (1H MRS): A practical guide for the clinical neuroscientist. Brain Imaging in Behavioral Medicine and Clinical Neuroscience, Cohen, R.A. & Sweet, L.H. Eds., New York, NY: Springer.
Haley, A.P., Eagan, D.E., Gonzales, M.M., Biney, F.O., Cooper, R.A. (2011) fMRI of working memory reveals frontal hypoactivation in middle-aged adults with cognitive complaints. Journal of the International Neuropsychological Society, 17(5), 915-24.
Haley, A.P. (2011) Subclinical atherosclerosis and neuronal integrity in midlife. International Atherosclerosis Society [On-line].
Hoth, K.F., Gonzales, M.M., Tarumi, T., Miles, S.C., Tanaka, H., Haley, A.P. (2011) fMRI evidence of altered functional activation in Metabolic Syndrome. American Journal of Neuroradiology, 32(3), 541-547.
Gonzales M.M.*, Tarumi T, Eagan D, Tanaka H, Biney, F.O., Haley AP. (2011) Current serum lipoprotein levels and fMRI Response to working memory in midlife. Dementia and Geriatric Cognitive Disorders, 31(4), 259-267.
Tarumi, T.*, Shah, F., Tanaka, H., Haley, A.P. Association between central artery stiffness and cerebral perfusion in deep subcortical gray and white matter. American Journal of Hypertension, 24(10), 1108-13.
Haley, A.P. and Knight-Scott, J. Proton magnetic resonance spectroscopy (1H MRS): A practical guide for the clinical neuroscientist. Brain Imaging in Behavioral Medicine and Clinical Neuroscience, Cohen, R.A. & Sweet, L.H. Eds., New York, NY: Springer.
Haley, A.P., Gonzales, M.M., Tarumi, T., Miles, S., Goudarzi, K., Tanaka, H. (2010) Elevated cerebral glutamate and myo-inositol levels in cognitively normal middle-aged adults with Metabolic Syndrome. Metabolic Brain Disease, 25(4), 397-405.
Gonzales, M.M.*, Tarumi, T., Tanaka, H., Sugawara, J., Swann-Sternberg, T., Goudarzi, K., Haley, A.P. (2010) Functional imaging of working memory and peripheral endothelial function in middle-aged adults. Brain and Cognition, 73, 146-151.
Haley, A.P., Tarumi, T., Gonzales, M.M., Sugawara, J., Tanaka, H. (2010) Subclinical atherosclerosis is related to lower neuronal integrity in middle-aged adults: a 1H MRS study. Brain Research, 1344, 54-61.
Gonzales, M.M.*, Tarumi, T., Miles, S., Tanaka, H., Shah, F., Haley A.P. (2010) Insulin sensitivity as a mediator of the relationship between body mass index and working memory-related brain activation. Obesity,18, 2131-2137.
Cohen, R.A., Poppas, A., Forman, D.E., Hoth, K.F., Haley, A.P., Gunstad, J., Jefferson, A.L., Tate, D.F., Paul, R.H., Sweet, L.H., Ono, M., Jerskey, B., Gerhard-Herman, M. (2009) Vascular and cognitive functions associates with cardiovascular disease in the elderly. Journal of Clinical and Experimental Neuropsychology, 31(1), 96-110.
Jerskey, B.A., Cohen, R.A., Jefferson, A.L., Hoth, K.F., Haley, A.P., Gunstad, J.J., Forman, D.E., Sweet, L.H., Poppas, A. (2009) Sustained attention is associated with systemic reduction of blood flow. Journal of the International Neuropsychological Society, 15(1), 137-141.
Stanek, K.M., Gunstad, J., Paul, R.H., Poppas, A., Jefferson, A.L., Sweet, L.H., Hoth, K.F., Haley, A., Forman, D.E., Cohen, R.A. (2009) Longitudinal cognitive test performance in older adults with cardiovascular disease: Evidence for improvement in heart failure. Journal of Cardiovascular Nursing, 24(3), 192-197.
Sweet, L.H., Haley, A.P., Cohen, R.A. Functional Neu
roimaging in Cardiovascular Disease. Heart Disease and the Brain, Cohen, R.A. & Gunstad, J. Eds., Oxford University Press.
Gunstad, J., Keary, T., Poppas, A., Paul, R., Jefferson, A.L., Sweet, L., Hoth, K., Haley, A., Forman, D., Cohen, R. (2009) Blood pressure and cognitive function in older adults with cardiovascular disease. International Journal of Neuroscience, 119, 2228-2242.
Haley, A.P., Hoth, K.F., Gunstad, J, Paul, R.H., Jefferson, Tate, D.T., Ono, M., Jerskey, B.A., Poppas, A., Sweet, L.H., Cohen, R.A. (2009) Subjective cognitive complaints relate to white matter hyperintensities and future cognitive decline in patients with cardiovascular disease.American Journal of Geriatric Psychiatry, 17(11), 976-985.
McCaffery, J.M., Haley, A.P., Sweet, L.H., Phelan, S., Raynor, H.A., Del Parigi, A., Cohen, R., Wing, R.R. (2009) Differential fMRI response to food pictures among successful weight loss maintainers relative to normal weight and obese controls. American Journal of Clinical Nutrition, 90(4), 928-934.
Irani, F., Sweet, L., Haley, A., Gunstad, J., Jerskey, B., Mulligan, R.C., Jefferson, A., Poppas, A., Cohen, R. (2009) An fMRI study of verbal working memory, cardiac output, and ejection fraction in elderly patients with cardiovascular disease. Brain Imaging and Behavior, 3, 350-357.